1.—I'm sorry to trouble you,madam..—_______D.What seems to be the problem?61.—I’m sorry to trouble you,madam..—_______A.What for?B.My pleasure.C.It’s no matter.D.What seems to be the problem?

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1.—I'm sorry to trouble you,madam..—_______D.What seems to be the problem?
61.—I’m sorry to trouble you,madam..—_______
A.What for?B.My pleasure.
C.It’s no matter.D.What seems to be the problem?

你是在语境中遇到的问题,比如你遇到问题,请教对方,于是说I am sorry to trouble you.对方于是问道,what seems to be the problem?
what seems to be the problem?的意思是“你有什么问题吗?”

很抱歉麻烦你,夫人.
有什么问题吗?